factory Octreotide Acetate 83150-76-9 in China CAS NO.83150-76-9

factory Octreotide Acetate 83150-76-9 in China

Acetate octreotide is a synthetic octetide compound, for 14 peptide human growth inhibitor analogue, acetate octreotide has a similar pharmacological effect to natural hormones, but its inhibition of growth hormone, glucose glucose, insulin has a stronger role. Similar to growth inhibitors, acetate octreotide can also inhibit LH's response to GnRH, reduce visceral blood flow, inhibit the secretion of 5-HT, gastroprogenes, vascular active intestinal peptides, proteases, gastrodynamics, and glucose glucose.

Application of acetate octreotide in the treatment of bleeding in the digestive tract
1. High-pressure bleeding of the door veins

Patients with hepatitis, liver cirrhosis history of gastrointestinal bleeding first consider the veins of high-pressure esophagus, gastric vein rupture bleeding. High pressure in the door veins can lead to rupture bleeding in the esophagus, the veins at the bottom of the stomach, and hypertensive gastric diseases in the veins.

Clinically, use a three-cavity two-cystic tube compression to stop the bleeding/ endoscopic sclerosis injection or sting treatment / through the neck vein hepatic endovenous-body venous shunt.

Acetic acid octreotide causes the abdominal cavity visceral arteries to contract, and the blood flow to the gut decreases by 25%-35%

0.6mgq12h (0.05mg/h) continuous intravenous drip, pumped into the course of 5 days

2. Treatment of bleeding from peptic ulcers

Inhibits the secretion of stomach acid, gastric progenitors and gastric proteases;

Acetic acid octreotide combined with omeprazole, than the simple use of omeprazole hemorrhage is higher, corresponding to the radical and acute ulcer bleeding hemorrhagic hemorrhage effect is obvious. Gastrointestinal ulcer bleeding is preferred under endoscopic treatment, followed by support treatment.

0.1mgq8h veins are continuously pumped into the course of treatment for 3-5 days.